Expression of Metallothionein I/II and Ki-67 Antigen in Graves' Disease
نویسندگان
چکیده
منابع مشابه
Expression of metallothionein and Ki-67 antigen in GISTs of different grade of malignancy.
BACKGROUND Metallothioneins (MTs) are low molecular weight proteins (6-7 kDa), which have been shown to regulate zinc ion homeostasis. MTs exert anti-apoptotic and pro-proliferative effect on cancer cells. Overexpression of MT-I and MT-II isoforms has been noted in many malignant tumors, but the role of their expression in gastrointestinal stromal tumors (GISTs) remains unclear. OBJECTIVES Th...
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Thyroid carcinomas are the most frequently occurring tumours in the endocrine system. Metallothioneins (MT) and Ki-67 proteins are present in intensely proliferating cells, and their expression has been observed in numerous tumours, including thyroid tumours. The purpose of this study was to analyse the relationship between intensity of MT expression and Ki-67 antigen on one hand and histologic...
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BACKGROUND This study aimed at the evaluation of the expression of metallothionein (MT) in laryngeal carcinoma and its correlation with the expression of Ki-67 antigen and p53 protein and selected clinical and pathological variables in view of their potential prognostic significance. MATERIALS AND METHODS Sixty-five laryngeal cancer patients were retrospectively analysed. Expression of MT, Ki...
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The study aimed at determining levels of metallothionein (MT) and Ki-67 antigen expression in adenocarcinomas of large intestine and examining relation of the expression levels with various clinical and pathological variables. The studies were performed on 81 cases of large intestine adenocarcinoma. Using immunocytochemistry, expressions of MT (positive reaction in 73 cases) and of Ki-67 (posit...
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ژورنال
عنوان ژورنال: Anticancer Research
سال: 2018
ISSN: 0250-7005,1791-7530
DOI: 10.21873/anticanres.13059